Prior extended daily access to cocaine elevates the reward threshold in a conditioned place preference test

ZI Su, J Wenzel, A Ettenberg… - Addiction biology, 2014 - Wiley Online Library
… of the current experiment suggest that prior extended access to cocaine self-administration
diminished the reward value of the drug and thus a higher dose of cocaine was needed to …

Repeated exposure to cocaine during adolescence enhances the rewarding threshold for cocaineconditioned place preference in adulthood

L Caffino, F Moro, F Mottarlini, G Targa… - Addiction …, 2021 - Wiley Online Library
… to a rewarding dose of cocaine (10 mg/kg) elevating the … induced cocaine seeking in rats
after extended withdrawal from … If this holds true, our findings are in agreement with a previous

Assessment of cocaine-induced behavioral sensitization and conditioned place preference in mice

LN Smith, RD Penrod, M Taniguchi… - JoVE (Journal of …, 2016 - jove.com
… In rodents, reward experience and contextual associations … 1) pre-test preference scores
for the (eventual) cocaine-paired … - and post-tests, increases in the cocaine-paired side can be …

Pre-treatment with high doses of cocaine decreases the reinforcing effects of cocaine in the conditioned place preference paradigm

C Manzanedo, MP Garcia-Pardo, M Rodríguez-Arias… - Neuroscience …, 2012 - Elsevier
… the conditioned rewarding effects of threshold doses of cocaine, … or cannabinoids increases
the rewarding effects of the former … they had undergone a prolonged period of cocaine self-…

Initial rewarding effects of cocaine and amphetamine assessed in a day using the single‐exposure place preference protocol

AH Runegaard, KL Jensen… - European Journal of …, 2019 - Wiley Online Library
… DA signalling prior to drug exposure affects either reward-… The most commonly used models
are the conditioned place preference (… , is targeting dopaminergic neurons and increases

Effects of intraaccumbens administration of SCH‐23390 on cocaine‐induced locomotion and conditioned place preference

DA Baker, RA Fuchs, SE Specio, TV Khroyan… - Synapse, 1998 - Wiley Online Library
… necessary for the rewarding effects of cocaine since blockade of … -23390 prior to cocaine
administration did not differ from cocaine con… The present results further extend findings from self…

Low and high locomotor responsiveness to cocaine predicts intravenous cocaine conditioned place preference in male Sprague–Dawley rats

RM Allen, CV Everett, AM Nelson, JM Gulley… - Pharmacology …, 2007 - Elsevier
… initial cocaine locomotor responsiveness and cocaine rewardconditional responding is
not surprising given our previous … sensitization involving increases in the ability of cocaine to …

Role of accumbens BDNF and TrkB in cocaine-induced psychomotor sensitization, conditioned-place preference, and reinstatement in rats

A Bahi, F Boyer, JL Dreyer - Psychopharmacology, 2008 - Springer
… BDNF was previously shown to be involved in cocaine reward … Furthermore, acute cocaine
administration increases striatal … Our data clearly support previous observations and further …

… -paired cues in a rat gambling task increases sensitivity to cocaine self-administration and suppresses dopamine efflux in nucleus accumbens: support for the reward …

JMN Ferland, TJ Hynes, CD Hounjet… - Journal of …, 2019 - Soc Neuroscience
… Animals underwent consecutive daily rGT and cocaine self-… In Experiment 2, locomotor
testing was first performed before … , but levers would remain extended and responses monitored. …

Social reward-conditioned place preference: a model revealing an interaction between cocaine and social context rewards in rats

KJ Thiel, AC Okun, JL Neisewander - Drug and alcohol dependence, 2008 - Elsevier
… sub-threshold parameters for establishing social reward- and … effect of day (F(1,33) = 7.87,
p < .01) due to small increases in … absence of a playmate prior to conditioning, and therefore, …